SDMINP

Record added by Jurg Ott (the original Rockefeller list)

Full Name

Step-Down MIN P-value

Version

1.0 (December 2005)

Description

SDMinP is an easy-to-use program for fast calculation of empirical and adjusted p-values for correlated and uncorrelated hypotheses in multiple testing experiments. It is based on the Free Step-Down Resampling Method for controlling the Family Wise Error Rate, originally proposed by Westfall and Young (1993), and implements a variation of the efficient algorithm of Ge et al. (2003), in which the originally necessary re-sampling effort was reduced considerably and the method made computationally more feasible. The program is independent of the underlying test statistic and works with provided observed and permutation test statistics.

Author

  • Markus Obreiter

  • Lars Beckmann (email: l.beckmann@dkfz.de)

    URL

    http://www.dkfz.de/SDMinP/

    Language

    Python 2.3.5

    OS

    UNIX, Linux, MS-Windows

    Reference

    Obreiter, Fischer, Chang-Claude, Beckmann (2005), “SDMinP: a program to control the family wise error rate using step-down minP adjusted p-values”, Bioinformatics, 21(14):3183-3184.