SOLAR

Record added by Jurg Ott (the original Rockefeller list)

Full Name

Sequential Oligogenic Linkage Analysis Routines

Version

4.0.7 (December 2006).

Description

OLAR is a flexible and extensive software package for genetic variance components analysis, including linkage analysis, quantitative genetic analysis, and covariate screening. Operations are included for calculation of marker-specific or multipoint identity-by-descent (IBD) matrices in pedigrees of arbitrary size and complexity, and for linkage analysis of quantitative traits which may involve multiple loci (oligogenic analysis), dominance effects, and epistasis.

Author

  • John Blangero (john@darwin.sfbr.org)
  • Kenneth Lange
  • Laura Almasy (almasy@darwin.sfbr.org)
  • Tom Dyer (tdyer@darwin.sfbr.org)

  • Charles Peterson (charlesp@darwin.sfbr.org).

    URL

    http://www.sfbr.org/Departments/genetics_detail.aspx?p=37

    Language

    FORTRAN, C, C++, TCL

    OS

    UNIX(Solaris 7-10/Solaris x86 8-9/Digital Unix 4.0e/SG Irix), Linux, MacOS, MS-Windows

    EXE

    solar, ibdprep, ibdmat, relate, multipnt

    Reference

  • Blangero, Almasy (1996), “SOLAR: sequential oligogenic linkage analysis routines”, Population Genetics Laboratory Technical Report No. 6, Southwest Foundation for Biomedical Research, San Antonio, TX 78228.

  • Almasy, Blangero (1998), “Multipoint quantitative-trait linkage analysis in general pedigrees”, American Journal of Human Genetics, 62(5):1198-1211 (1998)