DHSMAP

Record added by Jurg Ott (the original Rockefeller list)

Full Name

Decay of Haplotype Sharing MAPping software

Version

2.0 (October 18, 2001)

Description

DHSMAP is a program for fine-mapping of qualitative traits by linkage disequilibrium. Given a set of marker haplotypes or genotypes from affected individuals, haplotypes or genotypes from appropriately selected controls, and a genetic map of the markers at which both sets of individuals are typed, DHSMAP estimates the location of the trait-associated variant by maximum likelihood or maximum quasi-likelihood.

Author

  • Andrew Strahs
  • Kenneth Wilder

  • Mary Sara McPeek (University of Chicago)

    URL

    http://galton.uchicago.edu/~mcpeek/software/dhsmap/

    Language

    C++

    OS

    UNIX(Solaris/..), Linux

    EXE

    dhsmap.solaris, dhsmap.linux

    Reference

    McPeek and Strahs (1999), “Assessment of linkage disequilibrium by the decay of haplotype sharing, with application to fine-scale genetic mapping”, American Journal of Human Genetics, 65(3):858-875