SIMLA

Record added by Jurg Ott (the original Rockefeller list)

Full Name

SIMulation of pedigree data for Linkage and Association studies

Version

2.3 (Oct 2003)

Description

SIMLA is a SIMulation program that generates data sets of families for use in Linkage and Association studies. It allows the user flexibility in specifying marker and disease placement, locus heterogeneity, disequilibrium between markers and between markers and disease loci. Output is in the form of a LINKAGE pedigree file and is easily utilized, either directly or with minimal reformatting, as input for various genetic analysis packages

Author

  • Elizabeth Hauser

  • Eden Martin

  • Meredyth Bass

URL

http://wwwchg.duhs.duke.edu/software/simla.html

Language

C++

OS

UNIX(Solaris), Linux

EXE

simla2.3

Reference

  • MP Bass, ER Martin, ER Hauser(2002), Am J Hum Genet, suppl 71:569.

  • MP Bass, ER Martin, ER Hauser (2004), “Pedigree generation for analysis of genetic linkage and association”, Proceedings of the Pacific Symposium on Biocomputing, pp.93-103.