SIBLINK

Record added by Jurg Ott (the original Rockefeller list)

Version

3.0

Description

SIBLINK allows the user to perform multipoint linkage analysis based on estimated IBD sharing between affected sibpairs. IBD sharing is inferred from IBS status, given marker genotypes, frequencies, and locations. Resulting LOD scores are maximized across a grid of possible disease locations and IBD sharing vectors.

Author

  • Elizabeth Hauser

  • Mike Boehnke

  • William Duren

URL

http://wwwchg.duhs.duke.edu/software/siblink.html

Language

C++

OS

UNIX(Solaris), Linux

EXE

siblink3.0

Reference

  • ER Hauser, M Boehnke, SW Guo, N Risch (1996), Genetics Epidemiology. 13:117-137.

  • ER Hauser, M Boehnke M (1998), Biometrics, 54:1238-1246.