HPLUS

Record added by Jurg Ott (the original Rockefeller list)

Version

2.5

Description

HPlus is an analysis tool for performing haplotype estimation on genetic markers such as SNPs and microsatellites. It is able to handle datasets that include case-control status as well as covariates and marker location variables (such as gene name, chromosome location, etc).

Author

  • Sue Li

  • RJ Laws

  • LuePing Zhao (Fred Hutchinson Cancer Research Center)

URL

http://cougar.fhcrc.org/hplus/

OS

MS-Windows, Linux

Reference

  • Zhao, Li, Khalid (2003), “A method for assessing disease associations with SNP haplotypes and environmental variables in case-control”, American Journal of Human Genetics, 72(5):1231-1250

  • Li, Khalid, Carlson, Zhao (2003), “Estimating haplotype frequencies and standard errors for multiple single nucleotide polymorphisms”, Biostatistics, 4:513-522.