L-POP

Record added by Jurg Ott (the original Rockefeller list)

Version

Jan 2001

Description

L-POP detects population stratification in samples of unrelated individuals for whom a number of unlinked genotypes have been measured.

Using a latent class analysis model, population strata are defined such that unlinked markers are in Hardy-Weinberg equilibrium and linkage equilibrium within classes.

L-POP calculates the posterior probabilities for each individual belonging to each of K classes, which can be used to correct for spurious effects of population stratification in tests of association.

Author

  • Shaun Purcell

  • Pak Sham

URL

http://statgen.iop.kcl.ac.uk/lpop/

OS

MS-DOS

EXE

lpop