GENEPOOL

Record added by Jurg Ott (the original Rockefeller list)

Version

0.84

Description

GenePool is a software package that provides analysis tools for the detection of shifts in relative allele frequency between pooled genomic DNA from cases and controls using SNP-based genotyping microarrays. GenePool supports genotyping platforms from Affymetrix and Illumina.

Author

  • John Pearson (Translational Genomics Research Institute) (email: jpearson@tgen.org) David Craig (email: dcraig@tgen.org) Matt Huentelman (email: mhuentelman@tgen.org) Waibhav Tembe
  • Sotiris Mitranopolous

  • Nils Homer

    URL

    http://genepool.tgen.org/

    Language

    C/C++/Perl

    OS

    Linux, MacOS (should compile on most UNIX systems with gcc)

    EXE

    gpcommand, gpextract, gpanalyze

    Reference

    Pearson, Huentelman, Halperin, Tembe, Melquist, Homer, Brun, Szelinger, Coon, Zismann, Webster, Beach, Sando, Aasly, Heun, Jessen, Kolsch, Tsolaki, Daniilidou, Reiman, Papassotiropoulos, Hutton, Stephan, Craig (2007), “Identification of the genetic basis for complex disorders by use of pooling-based genomewide single-nucleotide-polymorphism association studies”, American Journal of Human Genetics, 80:126-139